Recently, the research identified a new issue called the CEDS or Clinical Endocannabinoid Deficiency Syndrome. For patients with chronic issues, this syndrome can worsen their condition. Let’s first understand the endocannabinoid system and how it functions.

The Endocannabinoid system is an internal organ in the human body that connects cannabinoid receptors across the body. CB1 and CB2 are the only known ones, but there are still more cannabinoid receptors to discover.

• CB1 is in the brain, connective tissues, nervous system, glands, gonads, and several other parts. • CB2 majorly resides in your immune system.

The human body produces cannabinoids, which are called endocannabinoids. Two endocannabinoids are well-researched - anandamide and the 2-AG [2-Arachidonoylglycerol]. Both 2-AG and anandamide are the body’s version of CBD and THC but their activity differs. THC [tetrahydrocannabidiol] and CBD [Cannabidiol] are present in the cannabis plant and are called phytocannabinoids.

The Endocannabinoid system is responsible for the state of homeostasis or balance in the body. ECS handles functions like healing, cell development, pain mitigation, and mood. Research has revealed that CBD helps the ECS but it is still unclear how this is done. As there is still a ban on the use of cannabis, the scope for research is still limited.

However, due to public demand, a Farm Bill was passed and CBD hemp oil has been legalized at the state level. Make sure to look for quality cannabis brands to enjoy the benefits. Just CBD Store is an established supplier of cannabidiol products in a variety of forms like a tincture, sublingual, topical, oil, edibles, and more.

What is Clinical Endocannabinoid Deficiency Syndrome?

CEDS is a situation, where a person lacks critical endocannabinoids and can experience pain where it shouldn’t be. Some common diseases that fit a pattern include irritable bowel syndrome, migraines, and fibromyalgia. All are hyperalgesic syndrome, which mean the pain is excessive and something is driving the pain.

Genetics can be the cause of migraines but its connection with possible CEDS cannot be established because there is no research and still CEDS is not validated. The research was studying migraines, IBS, and fibromyalgia - all conditions are associated with obesity and malnutrition. There is evidence revealing that diet can optimistically influence the balance of your ECS.

• Migraines - People suffering from migraines are hypersensitive to light and sound. Endocannabinoids manage the pain level, so it is suggested that CEDs can be the reason for migraines.

• Fibromyalgia - It is a chronic pain that affects the entire body. The amount of pain is disproportionate like a migraine. An increase in pain sensitivity can be due to the absence of endocannabinoid or reduced function of endocannabinoid.

• Irritable Bowel Syndrome - ECS controls the tiny muscular contractions, which help the bowel move within the intestines.

CEDS treatment

The practical solution to deal with the lack of endocannabinoids is to supply cannabinoids from the outside. It is just like taking vitamin supplements. CBD does not bind with CB1 and CB2 receptors but has an optimistic impact on anandamide.

CBD can act as an anandamide reuptake and halt the inhibitors. CBD proficiently prevents collapse and loss of anandamide. People who struggle with a lack of endocannabinoids can acquire more anandamide.